Diagnostic performance study of an antigen microarray for the detection of antiphospholipid antibodies in human serum
Aline R. Schindler, Oliver Bleher, Markus A. Thaler, Carmen J. Kocot, Udo Steigerwald, Günther Proll, Günter Gauglitz, and Peter B. Luppa Abstract Background: The parallelization of clinically relevant antigens in a microarray format is of growing importance due to the ability to measure multiple antigen-antibody interactions. With the development of a microarray for the detection […]
Development of a new parallelized, optical biosensor platform for label-free detection of autoimmunity-related antibodies
Oliver Bleher, Aline Schindler, Meng-Xin Yin, Andrew B. Holmes, Peter B. Luppa, Günter Gauglitz, Günther Proll Abstract Autoimmune diseases are characterized by the presence of autoantibodies in serum of affected patients. The heterogeneity of autoimmune relevant antigens creates a variety of different antibodies, which requires a simultaneous detection mode. For this reason, we developed a […]