Functionalization of silicon oxide using supercritical fluid depositionof 3,4-epoxybutyltrimethoxysilane for the immobilization of amino-modified oligonucleotide

Jordi Rull, Guillaume Nonglaton, Guillaume Costa, Caroline Fontelaye, Caroline Marchi-Delapierre, Stéphane Ménage, Gilles Marchand Abstract The functionalization of silicon oxide based substrates using silanes is generally performed through liquid phase methodologies. These processes involve a huge quantity of potentially toxic solvents and present some important disadvantages for the functionalization of microdevices or porous materials, for […]

Spatially controlled immobilisation of biomolecules: A complete approach in green chemistry

Eva Grinenval, Guillaume Nonglaton, Françoise Vinet. Abstract The development of “green” sensors is a challenging task in the field of biomolecule sensing, for example in the detection of cardiac troponin-I (cTnI). In the present work a complete approach in green chemistry was developed to create chemically active patterns for the immobilisation of biological probes. This […]