Grafting of Metallacarboranes onto Self-Assembled Monolayers Deposited on Silicon Wafers

Emilio José Juarez-Pérez, Michel Granier, Clara Vinas, P. Hubert Mutin, and Rosario Nunez Abstract The recent emergence of applications of carboranes as materials for nanotechnology and pharmacophores in drug design has greatly expanded the potential use of boron clusters. The cobaltabisdicarbollide anion [3,3-Co(1,2-C2B9H11)2] is a sandwich complex characterized by an extraordinary chemical and thermal stability. […]

Surface modification of calcium carbonate with phosphonic acids

Wassim El Malti, Danielle Laurencin, Gilles Guerrero, Mark E. Smithb and P. Hubert Mutin Abstract The surface of precipitated calcite particles was modified by reaction with phosphonic acids(phenylphosphonic acid and dodecylphosphonic acid) in organic solvents, tetrahydrofuran (THF) andethanol. The reaction kinetics and adsorption isotherms were determined. Under appropriateconditions, dense phosphonate monolayers were deposited at the […]

Covalent functionalization of TiO2 nanotube arrays with EGF and
BMP-2 for modified behavior towards mesenchymal stem cells

Sebastian Bauer, Jung Park, Andreas Pittrof, Yan-Yan Song,Klaus von der Markb and Patrik Schmuki Abstract In the present work we show the covalent immobilization of two bioactive molecules, epidermal growth factor (EGF) and bone morphogenetic protein-2 (BMP-2), on TiO2 nanotube surfaces and the resulting influence on the behavior of mesenchymal stem cells. Covalent immobilization of […]