Multifunctional magnetic nanoparticles for enhanced intracellular drug transport
C. Tudisco, M. T. Cambria, F. Sinatra, F. Bertani, A. Alba, A. E. Giuffrida, S. Saccone, E. Fantechi, C. Innocenti, C. Sangregorio, E. Dalcanale and G. G. Condorelli Abstract In this paper we report the synthesis and characterization of biocompatible multi-functional magnetic nanoparticles (MNPs) able to enhance the intracellular transport of N-methylated drugs. The Fe3O4 […]
Functionalization of PEGylated Fe3O4 magnetic nanoparticles with tetraphosphonate cavitand for biomedical application
C. Tudisco, F. Bertani, M.T. Cambria, F. Sinatra, E. Fantechi, C. Innocenti, C. Sangregorio, E. Dalcanale and G. G. Condorelli Abstract In this contribution, Fe3O4 magnetic nanoparticles (MNPs) have been functionalized with a tetraphosphonate cavitand receptor (Tiiii), capable of complexing N-monomethylated species with high selectivity, and polyethylene glycol (PEG) via click-chemistry. The grafting process is […]