Bioconjugation on cube-octameric silsesquioxanes

Sebastian Fabritz, Sebastian Hörner, Olga Avrutina and Harald Kolmar. Abstract Small, compact, and highly symmetric cube-octameric silsesquioxanes have recently attracted increased attention as scaffolds for tailor-made bioconjugates. The expanded arsenal of effective conjugation methods (CuAAC, TEC, oxime ligation) allows one to decorate these nanoparticles bearing up to eight addressable organic substituents, with a wide range […]